Invited Speech Announcement

Personalized Medicine Based

Drug Discovery and Therapy

因人施藥

Academician Chih-Ming Ho, Ph.D.

10/27/2015, Tuesday, 1400-1600

Place: Room 108, Eng. I Building

Abstract

Patient response rates to chemotherapy are fairly low in cancer treatment, often due to human diversity and cancer heterogeneity.  For example, the response rate for lung cancer is about 25% and only 10% for hepatoma. Therefore, personalized medicine is necessary to improve treatment efficacy/response rate as well as safety by providing precisely tailored patient therapy. 

To address these major challenges, recent technology developments have enabled the precise determination of which medicines may be most effective for a single patient based on his/her specific phenotypic expression. Engineering feedback system control (FSC.X) techniques can realize unprecedented levels of adaptability to rapidly home in on an optimized drug-dose combination based on the measured end-point phenotype of a specific patient. The emergence of phenotypic personalized medicine (PPM) can not only customize therapy to one specific patient. PPM will intersect medical and biological sciences with technology development and will catalyze revolutionary progress towards truly personalized medicine.

Bio

Chih-Ming Ho received B.S. from National Taiwan University and Ph.D. from The Johns Hopkins University.  Currently, he holds the Ben Rich-Lockheed Martin Chair Professor and Distinguished Professor in UCLA School of Engineering.  He served as UCLA Associate Vice Chancellor for Research from 2001 to 2005.

           His research interests are in personalized medicine, micro/nano fluidics, and turbulence.  In 1997, Dr. Ho was inducted as a member of the National Academy of Engineering. In the next year, he was elected as an Academician of Academia Sinica.  In 2014, Dr. Ho received Doctor of Engineering Honoris Causa from Hong Kong University of Science and Technology. Dr. Ho holds ten honorary chair professorships including the Einstein Professorship from Chinese Academy of Science.  Dr. Ho was elected Fellow of the American Physical Society, American Institute for Medical and Biological Engineering American Institute of Aeronautics and Astronautics as well as 3M-Nano Society.

           On the international level, he has served on advisory panels to provide assistance to many countries and regions including China, France, Hong Kong, Israel, Japan, Korea, Singapore, Switzerland, Taiwan, Thailand and United Kingdom, on the developments of medicine, engineering and science.

·     Contact: Prof. Da-Jeng Yao, Institute of NanoEngineering and MicroSystems (iNEMS), National Tsing Hua University

·     Tel: (03) 574-2850, Email: djyao@mx.nthu.edu.tw  

·      主辦單位：國立清華大學 奈米工程與微系統所/動力機械工程學系